We discuss advanced optical and nanophotonic techniques for detecting single biomolecules with extremely high sensitivity, down to single-molecule levels. We describe and show how modern optical methods — including fluorescence imaging, plasmonics, and nanostructure-enhanced sensing — can be used to visualize single molecules, detect ultra-low analyte concentrations directly in complex…
On February 7, 2025, on the eve of Russian Science Day, the first ceremony of presenting the “Person of Science” award from the Office of the Council of Deputies of the Troitsk Urban District in Moscow, a science city of the Russian Federation, was held at the Glinka Children’s Art…
We reports the development of a miniaturized optoelectronic component in which a gallium phosphide (GaP) nanowire (NW) serves simultaneously as an optical waveguide and an electrically-driven light source. By doping the GaP nanowire differently — either with Be (p-type) or Si (n-type) — we demonstrate integrated visible-range electroluminescence within a…
We investigate how strong light–matter interactions can be used to engineer the radiative (light emission) properties of complex nanoscale systems composed of fluorescent dye molecules embedded in a polydopamine matrix and coupled to metallic nanoparticles. Polydopamine is a common biocompatible adhesive material, but it typically quenches fluorescence of embedded dyes…
In 2024, the Russian Academy of Sciences celebrates its 300th anniversary since its founding. Victor Balykin, head of the spectroscopy laboratory at the Institute of the Russian Academy of Sciences, were honored with this special award in conjunction with the 300-year anniversary celebrations.This medal was awarded to the outstanding scientists…
The paper presents a novel optical microscopy method for directly detecting infectious SARS-CoV-2 viral particles in clinical samples by counting spike proteins on individual virions. Traditional virus detection techniques often measure viral genomes or specific proteins but cannot differentiate between infectious particles and non-infectious debris. We address this limitation by…
We have proposed, implemented and investigated a novel, efficient quantum emitter based on an atomic-sized Ag nanocluster in a plasmonic resonator. The quantum emitter enables the realization of: (1) ultra-bright fluorescence, (2) narrow-band emission down to 4 nm, (3) ultra-short fluorescence lifetime. The fluorescence cross-section of a quantum emitter is…
We report the design, fabrication, and experimental evaluation of a single-layer atom chip capable of continuous operation for laser cooling and trapping of neutral atoms. Traditional atom chips often use multilayer structures and operate in pulsed modes due to heat buildup from current-carrying wires. In this work, we optimized the…
We investigate how strong optical coupling between Cy7.5 dye molecules and gold (Au) nanorod plasmonic nanoparticles can influence the photobleaching (photodegradation) behavior of the dye. In typical conditions, dye molecules degrade when exposed to light due to transitions to reactive triplet states. However, when the dye molecules are strongly coupled…
We propose a new optical sensing method that enables real-time, ultra-fast, and extremely sensitive detection and imaging of single cardiac troponin-T (cTnT) molecules in complex biological samples like human blood serum. By combining an expanded laser excitation spot with fluorescent labeling strategies optimized for high photon collection, we overcome the…
We report the development and experimental demonstration of a femtosecond pulsed optical dipole trap for neutral atoms (rubidium) in which spectral filtering of the broadband laser light is used to significantly increase atom trapping lifetime. This spectral filtering removes near-resonant frequency components, reducing atom heating and allowing atoms to remain…
Congratulations to Daria Bykova on being awarded the Presidential Grant! The presidential scholarship is granted to talented young researchers who are tasked with addressing large-scale challenges, that involves creating technologies and products. For this purpose, the scholars possess the most important qualities—talent, knowledge, boldness—and receive support from mentors and the…
We congratulate Anton Afanasiev! His contribution to the development of our city (in promoting science among its residents) has been duly recognized. Anton’s photograph now adorns the city’s Board of Honor in Troitsk.
Junior Researcher of Laser Spectroscopy Department, Aleksey Kalmykov, has successfully defended his PhD dissertation titled “Ultrahigh Quality Nanoplasmonic Elements and Their Applications“. Scientific advisor – Dr. Viktor Balykin, Chief Research Scientist and Doctor of Physics and Mathematics at ISAN.
On February 9, 2024, in Troitsk, the 15th nomination for “Person of the Year” took place. The main ceremony of the city, summarizing the results of the Troitsk year – “Person of the Year”, is dedicated to Russian Science Day. Pavel Melentiev, a leading researcher at ISAN and Doctor of…
